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Latest App Notes & Case Studies

Genotoxic App Note Preview
App Note / Case Study

Confidence in Compliance: Genotoxic Impurity Analysis

Stringent safety requirements associated with the analyses of carcinogenic and mutagenic impurities can present significant challenges. Methods must achieve a high level of sensitivity and selectivity while maintaining sufficient sample throughput.
Protein Expression
App Note / Case Study

The New Gold Standard for Gene Therapy Protein Expression Potency Measurements

A major challenge preventing transformative gene therapies from reaching patients is the lack of fit-for purpose potency assays, which are some of the most important assays in an analytical package but are often the most complex and high-risk.
Successful SPR Assays
App Note / Case Study

Determining Real-Time Kinetics and Affinity

This compendium serves as a user-friendly reference for assay design on both bio-layer interferometry (BLI) and surface plasmon resonance (SPR) systems.
Oligos with Confidence
App Note / Case Study

Characterize Your Oligos With Confidence

Custom oligo synthesis can result in the formation of impurities. Hence, final products must be characterized to ensure they meet quality assurance and control standards.
Precision Oligo Sequencing
App Note / Case Study

A Simplified Method for Precise Oligo Sequencing

LC/MS methods can be used to analyze a wide range of oligo samples. However, ion-pairing reagents can interfere with analyses and present challenges in multi-use systems.
Antigen
App Note / Case Study

Fast Track Antigen-Specific B- and T-Cell Discovery

This application note demonstrates how Single Cell Immune Profiling and Barcode Enabled Antigen Mapping (BEAM) can be used to profile thousands of hPBMCs from a single donor.

CAR T: A Promising Cell Therapy for Cancer Treatment content piece image
App Note / Case Study

CAR T: A Promising Cell Therapy for Cancer Treatment

CAR-T cell therapy has emerged as one of the most promising novel treatments in the fight against cancer.
Understanding the Hidden Value of Quality content piece image
App Note / Case Study

Understanding the Hidden Value of Quality

Outsourcing quality management activities can save biomanufacturers time, money and resources. It can support scientists in bringing life-changing therapeutics to market swiftly and efficiently.
 Transitioning From RUO to cGMP for Clinical Trials content piece image
App Note / Case Study

Transitioning From RUO to cGMP for Clinical Trials

Both RUO and cGMP compliance play important roles in the drug discovery pipeline. However, meeting regulatory demands can be a challenge when accelerating new drugs to the clinic.
Streamline Your Metabolite Identification and Clearance Analyses  content piece image
App Note / Case Study

Streamline Your Metabolite Identification and Clearance Analyses

Discover an automated solution for the consolidation and ranking of your metabolite structures. Explore a workflow that utilizes both EAD and CID data for the most confident characterization and streamlined data acquisition.
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