Latest App Notes & Case Studies

COVID-19 is caused by the SARS-CoV-2 virus. While some patients have mild or asymptomatic illness, for others it can be fatal. Understanding the immune response to SARS-CoV-2 at a molecular level is useful for the development of effective vaccines, treatments and prognostic tests.

The specificity of fluorescence microscopy allows researchers to accurately observe and analyze biological processes and structures quickly and easily, even when using thick or large samples. However, out-of-focus fluorescence increases background, reduces contrast and makes accurate image segmentation more challenging.

Download this free application focus to learn more about innovative next-generation methylation detection systems.

Download this app note to discover a solution that can be used with any biotinylated affinity molecule, enables floatation-based separation of diverse targets as well as provides workflows that are exceptionally gentle on delicate analytes.

Wastewater testing offers valuable insight on community-level data for various analytes, including pathogens that are associated with infectious diseases. Quantitative reverse transcriptase PCR (qRT-PCR) is well suited for wastewater analyses of pathogens due to its sensitivity, scalability and cost-effectiveness.

One of the more promising types of cancer immunotherapy involves engineering immune cells to recognize and attack cancer.

Download this app note to discover a workflow that can detect SARS-CoV-2 RNA from challenging sample matrices and be used for the extraction and detection of other pathogens.

Glycosylation refers to the formation of linkages with glycosyl groups, covalently attaching a carbohydrate to another molecule. Antibody glycosylation is critical due to the role carbohydrates play in modulating effector functions which affect safety and efficacy of therapeutic antibodies.

The high resolution and scale that single cell analysis provides is revolutionizing drug discovery and development by introducing comparative, longitudinal and causal information that transforms our ability to understand biology and disease.

Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.