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Therapeutic Delivery – News and Features

3D reconstruction of a TARP.
News

Biologic “Patch” Activated by Natural Motion Could Help Fix Herniated Discs

The tension-activated repair patch used in animal trials plugs holes in discs in the spine like car tire patches and could prevent further disease progression.
Macrophages infiltrating a tumor spheroid.
News

Inability of Macrophages To Penetrate Tumors Could Explain Cell Therapy Failures

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy.
Six patient silhouettes with different colored pills inside each head
Article

A Personalized Approach Could Help To Tackle the Global AMR Crisis

Antimicrobial resistance (AMR) is threatening the effective treatment and prevention of a wide range of infections, with serious potential consequences for health and the economy. We spoke to Dr. Alaa Riezk, research associate at the Centre for Antimicrobial Optimisation (CAMO), Imperial College London, about the problem of usage and dosage of antimicrobials and AMR and how he and the team are working to address it.
A microscope image of breast cancer cells. MHC 1 is shown in red and the nuclei in blue.
News

Breast Cancer Cells Collaborate To Invade Surrounding Tissue

Researchers at Stanford have revealed a novel mechanism that breast cancer cells use to physically tear and deform the basement membrane barrier to break out and become invasive.
A side-by-side comparison of cells supported by the oxygenation device (left) and cells without the device support (right).
News

A Breath of Fresh Air Is Key for Cell-Based Therapies

In 2021, a University-led research team received a contract worth up to $33 million to develop an implantable “living pharmacy” to control the human body’s sleep/wake cycles. Now, the researchers have completed a major step toward achieving this.
A close up of a hand holding a syringe.
News

Neural Network Is Only Activated After Drug Injection Compared to Oral Drug Use

NIH study suggests the brain’s “salience network” is important for understanding substance use disorder, could be a future therapeutic target.
A woman applying cream to her hand.
News

“Super Melanin” Can Heal and Protect the Skin From Sun Damage

Imagine a skin cream that heals damage occurring throughout the day when your skin is exposed to sunlight or environmental toxins. That’s the potential of a synthetic, biomimetic melanin developed by scientists at Northwestern University.
A drawing of a spine on a brown clipboard.
News

ALS Drug May Be Effective for Spinal Cord Injuries, Small Study Suggests

A small clinical trial has indicated that the ALS drug Riluzole could also be effective for treating spinal cord injuries if taken within 12 hours post-injury.
Oversized syringe containing a vaccine being injected into the world.
Article

Next-Gen mRNA Technology: A Crucial Pandemic Preparedness Tool

Drew Burch discusses how next-gen mRNA technology is one of the most valuable tools to combat and control disease outbreaks and why continued investment in this field is crucial for maintaining our pandemic preparedness.
A close up of someone's eye.
News

Candidate Eye Infection Drug Sees Success in Trial

A drug candidate has been found to be highly effective in treating a rare sight-threatening eye infection in a new international clinical trial.
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